NSC126405
NSC126405 is a mTOR-DEPTOR inhibitor that binds to DEPTOR, prevents mTOR-DEPTOR binding and induces multiple myeloma (MM) cytotoxicity. NSC126405 can be utilized in cancer research[1].
Product Specifications
CAS Number
[17581-52-1]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc126405.html
Concentration
10mM
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(C(Cl)=C/1Cl)=C(Cl)C1=N\N
Molecular Formula
C5H2Cl4N2
Molecular Weight
231.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Shi Y, et al. Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells. Cancer Res. 2016 Oct 1;76 (19) :5822-5831.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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