LOX-1, Human, mAb 23C11 Antibody
Mouse monoclonal antibody to LOX-1
Product Specifications
Product Name Alternative
Lectin-like oxidized LDL receptor 1, Ox-LDL receptor 1, C-type lectin domain family 8 member A
Reactivity
Human
Cross Reactivity
Mouse - Yes
Immunogen
Fusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fcγ1 (LOX-1-muFc) produced in PEAK cells
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
For flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental settting.
Form
1 ml (100 μg/ml) 0.2 μm filtered antibody solution in PBS, containing 0.1% bovine serum albumin.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
FC: 10μg/ml antibody used on human peripheral blood myeloid DC and macrophages FS: antibody totally prevented Hsp70 binding to LOX-1-CHO but not mock-transfected CHO cells (Ref 1)
Tested Applications
FC, Functional Studies, IF
Preservative
Quantities >500 μg will be sent without preservatives and are carrier-free.
Isotype
Mouse IgG1
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