(±) -N-3-Benzylnirvanol

(±) -N-3-Benzylnirvanol is a racemic mixture of (+) -N-3-Benzylnirvanol and (-) -N-3-Benzylnirvanol. (+) -N-3-Benzylnirvanol and (–) -N-3-Benzylnirvanol are potent and selective cytochrome P450 inhibitors with Ki values of 0.25 and 5.3 μM for CYP2C19, respectively[1].

Product Specifications

CAS Number

[93879-40-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/racemic-n-3-benzylnirvanol.html

Purity

99.88

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1N(CC2=CC=CC=C2)C(C(C3=CC=CC=C3)(CC)N1)=O

Molecular Formula

C18H18N2O2

Molecular Weight

294.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Hisashi Suzuki, et al. (+) -N-3-Benzyl-nirvanol and (-) -N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19. Drug Metab Dispos. 2002 Mar;30 (3) :235-9.