Tiratricol (Standard)
Tiratricol (Standard) is the analytical standard of Tiratricol. This product is intended for research and analytical applications. Tiratricol is an orally available thyroid hormone analog that inhibits pituitary thyroid-stimulating hormone secretion. Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC50s of 20 μM and 32 μM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus (Flavivirus) . It can bind to the RdRp domain of the viral NS5 protein to hinder YFV replication.[2].
Product Specifications
CAS Number
51-24-1
Product Name Alternative
3,3',5-Triiodothyroacetic acid (Standard)
UNSPSC
12352005
Target
Flavivirus; Reference Standards; Thyroid Hormone Receptor; TNF Receptor
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/tiratricol-standard.html
Smiles
O=C(O)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1
Molecular Formula
C14H9I3O4
Molecular Weight
621.93
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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