Anti-SRY (Mouse Monoclonal)

Western blot (1:1000) and ELISA (1:2000~5000) . The Sex-Determining Region (SRY) is a gene that encodes a transcription factor that is a member of the high mobility group HMG-box family of DNA binding proteins.The gene is located on the short arm of the Y chromosome and has a gene map locus - Yp11.3.Common synonyms of the gene name are Testis Determining Factor (TDF) and Testis Determining Factor on Y (TDY) . The main function of the SRY protein is to initiate male sex determination as a transcriptional activator, which regulates a genetic switch in male development. The SRY HMG box recognizes DNA by partial intercalation in the minor groove. The SRY protein then binds to the DNA and distorts its shape (SRY protein in action) . In doing so, it regulates genes that control the development of the testes.

Western blot (1:1000) and ELISA (1:2000~5000) . The Sex-Determining Region (SRY) is a gene that encodes a transcription factor that is a member of the high mobility group HMG-box family of DNA binding proteins.The gene is located on the short arm of the Y chromosome and has a gene map locus - Yp11.3.Common synonyms of the gene name are Testis Determining Factor (TDF) and Testis Determining Factor on Y (TDY) . The main function of the SRY protein is to initiate male sex determination as a transcriptional activator, which regulates a genetic switch in male development. The SRY HMG box recognizes DNA by partial intercalation in the minor groove. The SRY protein then binds to the DNA and distorts its shape (SRY protein in action) . In doing so, it regulates genes that control the development of the testes.