Anti-Huntingtin

Western blot and IHC in lipid metabolic research. Huntingtin is a 350kDa protein that is mutated in Huntington's disease (HD) . The normal function of Huntingtin still remains uncertain but it has been suggested that it performs a necessary housekeeping function. The abnormal form of Huntingtin aggregates in vitro and forms neuronal intranuclear and cytoplasmic inclusions in HD patients. This antibody detects a 350KD band on western blots but also detects smaller degradation products_recover of Huntingtin in some tissue lysates.

Western blot and IHC in lipid metabolic research. Huntingtin is a 350kDa protein that is mutated in Huntington's disease (HD) . The normal function of Huntingtin still remains uncertain but it has been suggested that it performs a necessary housekeeping function. The abnormal form of Huntingtin aggregates in vitro and forms neuronal intranuclear and cytoplasmic inclusions in HD patients. This antibody detects a 350KD band on western blots but also detects smaller degradation products_recover of Huntingtin in some tissue lysates.