Uracil-DNA Glycosylase

<strong>Uracil-DNA Glycosylase</strong>_x000D_ <strong>Catalog number:</strong> B2016485_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 units_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> PCR, UDG_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kara H, Chazal N, Bouaziz S. Is Uracil-DNA Glycosylase UNG2 a New Cellular Weapon Against HIV-1? Curr HIV Res. 2019;17(3):148-160._x000D_ 2: Perkins JL, Zhao L. The N-terminal domain of uracil-DNA glycosylase: Roles for disordered regions DNA Repair (Amst). 2021 May;101:103077._x000D_ 3: Orndorff PB, Poddar S, Owens AM, Kumari N, Ugaz BT, Amin S, Van Horn WD, van der Vaart A, Levitus M. Uracil_DNA glycosylase efficiency is modulated by substrate rigidity Sci Rep. 2023 Mar 8;13(1):3915._x000D_ 4: Chang HL, Su KY, Goodman SD, Cheng WC, Lin LI, Yang YC, Chang SY, Fang WH. Uracil-DNA Glycosylase Assay by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Analysis J Vis Exp. 2022 Apr 22;(182):10.3791/63089._x000D_ 5: Zharkov DO, Mechetin GV, Nevinsky GA. Uracil_DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition Mutat Res. 2010 Mar 1;685(1-2):11-20._x000D_ 6: Schormann N, Zhukovskaya N, Bedwell G, Nuth M, Gillilan R, Prevelige PE, Ricciardi RP, Banerjee S, Chattopadhyay D. Poxvirus uracil_DNA glycosylase-An unusual member of the family I uracil_DNA glycosylases Protein Sci. 2016 Dec;25(12):2113-2131._x000D_ 7: Smith KR, Paul S, Dong Q, Anannya O, Oldenburg DG, Forrest JC, McBride KM, Krug LT. Uracil_DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues mSphere. 2023 Oct 24;8(5):e0027823._x000D_ 8: Wu M, Zhang L, Dong K, Gong Y, Liu X. A novel Family V uracil DNA_glycosylase from Sulfolobus islandicus REY15A DNA Repair (Amst). 2022 Dec;120:103420._x000D_ 9: Kulkarni RS, Greenwood SN, Weiser BP. Assay design for analysis of human uracil DNA_glycosylase Methods Enzymol. 2023;679:343-362._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33675849">10: Nguyen MT, Moiani D, Ahmed Z, Arvai AS, Namjoshi S, Shin DS, Fedorov Y, Selvik EJ, Jones DE, Pink J, Yan Y, Laverty DJ, Nagel ZD, Tainer JA, Gerson SL. An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation Prog Biophys Mol Biol. 2021 Aug;163:143-159. </a>_x000D_ _x000D_ <strong>Products Related to Uracil-DNA Glycosylase can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>