Cereblon inhibitor 2
Cereblon inhibitor 2 (compound 8) is a Cereblon inhibitor useful in solid tumor research, especially breast cancer[1].
Product Specifications
CAS Number
[2639380-62-2]
UNSPSC
12352005
Target
Apoptosis; Autophagy; Ligands for E3 Ligase
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cereblon-inhibitor-2.html
Purity
98.86
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=C2C(C(N(C3C(NC(CC3)=O)=O)C2)=O)=C1)NC4=CC=C(C)C(Cl)=C4
Molecular Formula
C22H21ClN4O4
Molecular Weight
440.88
References & Citations
[1]Alexander Flohr, et al. Isoindolinone compounds.US20220242846A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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