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BRD4 Inhibitor-34

BRD4 Inhibitor-34 (Compound 12a) is a BRD4 inhibitor with an IC50 of 24 μM[1].

Product Specifications

CAS Number

[1095051-68-5]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd4-inhibitor-34.html

Solubility

10 mM in DMSO

Smiles

O=C1SC=C(C2=CC=CC(Cl)=C2)N1

Molecular Formula

C9H6ClNOS

Molecular Weight

211.67

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Zhao L, et al. Fragment-based drug discovery of 2-thiazolidinones as inhibitors of the histone reader BRD4 bromodomain. J Med Chem. 2013;56 (10) :3833-3851.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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