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CCBR1 Rabbit Polyclonal Antibody

CCBR1 Rabbit Polyclonal Antibody

Product Specifications

Product Name Alternative

XCT_HUMAN; SLC7A11; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT; CCBR1; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

UniProt

Q9UPY5

Reactivity

Human, Mouse, Rat

Immunogen

KLH conjugated synthetic peptide derived from human xCT/CCBR1

Target

SLC7A11

Clonality

Polyclonal

Conjugation

Unconjugated

Purification

Affinity purified by Protein A

Concentration

1mg/ml

Dilution

WB=1:500-1000

Form

Liquid

Molecular Weight

57 kDa

References & Citations

Li, Meng et al. Melatonin Inhibits the Ferroptosis Pathway in Rat Bone Marrow Mesenchymal Stem Cells by Activating the PI3K/AKT/mTOR Signaling Axis to Attenuate Steroid-Induced Osteoporosis Oxid Med Cell Longev, 2022, 8223737 (2022), F Ye, Y Xu, X Zhu, Q Ding, Y Wang, S Lu, Y Chen The mechanism of E3 ubiquitin ligase HERC1 regulating ferroptosis in lung adenocarcinoma cells Cancer Genetics, (2025), Marco Strecker 1, Keren Zohar 2, Martin Böttcher 3, Thomas Wartmann 2, Henry Freudenstein 1, Maximilian Doelling 1, Mihailo Andric 1, Wenjie Shi 1, Or Kakhlon 4 5, Katrin Hippe 6, Beatrix Jahnke 7, Dimitrios Mougiakakos 3, Franziska Baenke 7 8, Daniel Stange 7 8, Roland S Croner 1, Michal Linial 2, Ulf D Kahlert 1 9 Patient-specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity Mol Oncol, (2025), Yulin Li et al. Mechanism of the enterobacterial metabolite sodium butyrate mediating ferroptosis to affect osteogenic ability of BMSCs in mice with estrogen deficiency-caused osteoporosis via the PTEN/PI3K/AKT pathway Apoptosis, (2025)

Pubmed id

36035224, 40988536, 41205030

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Prediction Reactivity

Mouse, Rat

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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