DCN1-UBC12-IN-4
DCN1-UBC12-IN-4 (compound 5p) is an inhibitor of DCN1-UBC12, with an IC50 greater than 10000 nM, and it exhibits anti-tumor activity[1].
Product Specifications
CAS Number
[26028-65-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dcn1-ubc12-in-4.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1=C(C=CC(=C1)Cl)C2=NNC(=N2)S
Molecular Formula
C8H6ClN3S
Molecular Weight
211.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Wenjuan Zhou, et al. Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction. Eur J Med Chem. 2021 May 5:217:113326.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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