Undecylenoyl phenylalanine

Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes, reduces hyperpigmentation and thus ameliorates melasma lesions and solar lentigines[1].

Product Specifications

CAS Number

[175357-18-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; Melanocortin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/undecylenoyl-phenylalanine.html

Purity

95.0

Solubility

DMSO : ≥ 116.67 mg/mL

Smiles

C=CCCCCCCCCC(N[C@H](C(O)=O)CC1=CC=CC=C1)=O

Molecular Formula

C20H29NO3

Molecular Weight

331.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Katoulis A, et al., A double-blind vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of melasma in females. J Cosmet Dermatol. 2014 Jun;13 (2) :86-90. |[2]Katoulis AC, et al., A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines. Clin Exp Dermatol. 2010 Jul;35 (5) :473-6.