6-Acetamidohexanoic acid

6-Acetamidohexanoic acid is a metabolite of hexamethylene bisacetamide (HY-124284) . 6-Acetamidohexanoic acid is less active than the parent compound HMBA and cannot induce cell differentiation[1][2][3].

Product Specifications

CAS Number

[57-08-9]

Product Name Alternative

Acexamic Acid; 6-Acetamidocaproic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6-Acetamidohexanoic-acid.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCCCCNC(C)=O

Molecular Formula

C8H15NO3

Molecular Weight

173.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Conley BA, et al. The effect of the monoamine oxidase inhibitor isocarboxazid on the canine metabolism of the cell-differentiating agent hexamethylene bisacetamide. Cancer Chemother Pharmacol. 1991;28 (1) :33-8. |[2]Liu F, et al. A Reactivity-Tunable Self-Immolative Design Enables Histone Deacetylase-Targeted Imaging and Prodrug Activation. Angew Chem Int Ed Engl. 2022 Nov 21;61 (47) :e202203243.|[3]Li L, et al. A carboxylesterase-activatable near-infrared phototheranostic probe for tumor fluorescence imaging and photodynamic therapy. RSC Adv. 2022 Dec 12;12 (54) :35477-35483.