6-Acetamidohexanoic acid
6-Acetamidohexanoic acid is a metabolite of hexamethylene bisacetamide (HY-124284) . 6-Acetamidohexanoic acid is less active than the parent compound HMBA and cannot induce cell differentiation[1][2][3].
Product Specifications
CAS Number
[57-08-9]
Product Name Alternative
Acexamic Acid; 6-Acetamidocaproic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-Acetamidohexanoic-acid.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CCCCCNC(C)=O
Molecular Formula
C8H15NO3
Molecular Weight
173.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Conley BA, et al. The effect of the monoamine oxidase inhibitor isocarboxazid on the canine metabolism of the cell-differentiating agent hexamethylene bisacetamide. Cancer Chemother Pharmacol. 1991;28 (1) :33-8. |[2]Liu F, et al. A Reactivity-Tunable Self-Immolative Design Enables Histone Deacetylase-Targeted Imaging and Prodrug Activation. Angew Chem Int Ed Engl. 2022 Nov 21;61 (47) :e202203243.|[3]Li L, et al. A carboxylesterase-activatable near-infrared phototheranostic probe for tumor fluorescence imaging and photodynamic therapy. RSC Adv. 2022 Dec 12;12 (54) :35477-35483.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Curated Selection
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