Zika virus E protein ectodomain (ZIKV-E)

Product Specifications

Background

Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (Family Flaviviridae) and was first described in 1947 in Uganda following blood analyses of sentinelRhesusmonkeys1. Until the 20thcentury, the African and Asian lineages of the virus did not cause meaningful infections in humans. However, in 2007, vectored byAedes aegyptimosquitoes, ZIKV caused the first noteworthy epidemic on the island of Yap in Micronesia2. Patients experienced fever, skin rash, arthralgia and conjunctivitis2. Zika is spread mostly by the bite of an infected Aedes species mosquito (Ae. aegypti and Ae. albopictus) . These mosquitoes bite during the day and night. Zika can be passed from a pregnant woman to her fetus. Infection during pregnancy can cause certain birth defects. There is no vaccine or medicine for Zika.

Structure Composition

Inclusion body;0.5mol Urea, PH=8

Swiss Prot

KU744693.1

Reactivity

E. coli Expression

Applications

Reseach

Dilution

Reseach

Purity

Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .

Molecular Weight

279bp;10kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Carrier:pET30a-ZIKV-E-His (C-term) Virus:Zika virus isolate VE_Ganxian

Host or Source

His-tag

Control Type

Zika virus E protein ectodomain, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.