Sicilian phlebovirus Nucleocapsid Protein (SFSV)
Product Specifications
Background
Sandfly fever Sicilian virus (SFSV) is one of the most widespread and frequently identified members of the genus Phlebovirus (order Bunyavirales, family Phenuiviridae) infecting humans. Being transmitted by Phlebotomus sandflies, SFSV causes a self-limiting, acute, often incapacitating febrile disease ("sandfly fever, " "Pappataci fever, " or "dog disease") that has been known since at least the beginning of the 20th century. Similarly to other pathogenic phleboviruses, SFSV suppresses the induction of the antiviral type I interferon (IFN) system in an NSs-dependent manner. SFSV NSs interfered with the TBK1-interferon regulatory factor 3 (IRF3) branch of the RIG-I signaling pathway but not with NF-κB activation.
Structure Composition
Soluble protein; PBS, PH=7.4
Swiss Prot
EF201822.1
Reactivity
E. coli Expression
Applications
Reseach
Dilution
Reseach
Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .
Molecular Weight
738bp;28kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Carrier:pET30a-SFSV-NP-His (C-term) Virus:Sandfly fever sicilian virus strain Sabin segment S
Host or Source
His-tag
Control Type
Sicilian phlebovirus Nucleocapsid Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
