Machupo mammarenavirus Nucleocapsid Protein (MACV)

Product Specifications

Background

Machupo virus (MACV) is a member of the NW complex of arenaviruses and is the causative agent of Bolivian hemorrhagic fever (HF) . Human infections generally result from exposure to chronically infected rodents (Calomys callosus), but human-to-human spread has been reported11. Bolivian HF is a febrile illness often associated with vascular leakage and occasional concomitant neurological manifestations. Infection can result in a systemic inflammatory response syndrome leading to multiple organ failure and death.

Structure Composition

Inclusion body;0.5mol Urea, PH=8

Swiss Prot

KM198592.1

Reactivity

E. coli Expression

Applications

Reseach

Dilution

Reseach

Purity

Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .

Molecular Weight

1692bp;62KDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Carrier: pET30a-MACV-NP-His (C-term) Virus: Machupo virus strain Carvallo segment S

Host or Source

His-tag

Control Type

Machupo mammarenavirus Nucleocapsid Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.