ACE2 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG,1mg/ml in PBS with 0.02% sodium azide,10% glycerol, pH7.2
Product Name Alternative
Angiotensin I converting enzyme 2; Severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; HCoV-19; SARS2; 2019-nCoV; COVID-19; COVID-19 virus; Human coronavirus 2019
Swiss Prot
Q9BYF1
Reactivity
COVID-19
Immunogen
Recombinant protein
Applications
WB
Dilution
WB: 1:2000~10000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ACE2 pAb detects endogenous levels of S-RCD protein.
Host or Source
Rabbit
Available Sizes
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