CD129/IL9R Recombinant Protein

Interleukin-9 (IL-9) functions to support the growth of helper T cells, megakaryoblastic leukemia cells, fetal thymocytes, erythroid and myeloid precursors and mast cells. The murine IL-9 receptor has been identified as a protein expressed on a T cell clone. Both the murine and human IL-9 receptor cDNAs have been isolated by expression cloning from the murine T cell clone TS1 and the human megakaryoblastic leukemia cell line MO7E, respectively. In addition, the cloning and analysis of the complete human IL-9 receptor genomic DNA has been reported. In this latter study, the IL-9R gene was shown to consist of 10 exons expressed over approximately 13.7 kb of DNA.

AGTGTGACCGGTGAAGGTCAGGGTCCGCGTAGCCGTACCTTCACCTGTCTGACCAATAATATTCTGCGCATTGATTGCCATTGGAGCGCCCCGGAACTGGGTCAGGGTAGCAGTCCGTGGCTGCTGTTCACCAGCAATCAGGCCCCGGGTGGTACCCATAAATGCATTCTGCGTGGCAGCGAATGCACCGTTGTGCTGCCGCCGGAAGCCGTGCTGGTTCCGAGTGATAACTTCACCATTACCTTCCATCATTGCATGAGTGGTCGTGAACAGGTTAGTCTGGTTGATCCGGAATATCTGCCGCGTCGTCATGTTAAACTGGATCCGCCGAGTGATCTGCAGAGCAATATTAGTAGCGGCCATTGCATTCTGACCTGGAGCATTAGCCCGGCCCTGGAACCGATGACCACCCTGCTGAGTTATGAACTGGCCTTCAAAAAACAGGAAGAAGCCTGGGAACAGGCACAGCATCGTGATCATATTGTTGGTGTGACCTGGCTGATTCTGGAAGCCTTCGAACTGGATCCGGGCTTCATTCATGAAGCCCGTCTGCGCGTTCAGATGGCAACCCTGGAAGATGATGTTGTGGAAGAAGAACGTTATACCGGCCAGTGGAGTGAATGGAGCCAGCCGGTGTGCTTCCAGGCACCGCAGCGTCAGGGCCCGCTGATTCCGCCTTGGGGTTGGCCG