CD180 Recombinant Protein
Product Specifications
Background
CD180/RP105 is a type-I transmembrane glycoprotein that is restricted to expression in mature B-cells. Research studies have shown that CD180 engages signaling cascades in mature B-cells that drive cell proliferation. Indeed, CD180 functions with TLR4 as an LPS receptor on B-cells and, upon binding LPS, transmits proliferation and survival signals that require the Vav family of guanine nucleotide exchange factors.
CAS Number
9000-83-3
Swiss Prot
Q99467
Modification Site
NdeI-XhoI
Expression System
Pet-22b (+)
Tag
His-tag
Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .
Solubility
PBS, 4M Urea, PH7.4
Molecular Weight
~66kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Host or Source
E.coli
AA Sequence
TGGGATCAGATGTGCATTGAAAAAGAAGCCAATAAAACCTATAACTGTGAAAATCTGGGCCTGAGTGAAATTCCGGATACCCTGCCGAATACCACCGAATTCCTGGAATTCAGCTTCAACTTCCTGCCGACCATTCATAATCGCACCTTCAGCCGCCTGATGAATCTGACCTTCCTGGATCTGACCCGCTGTCAGATTAATTGGATTCATGAAGATACCTTCCAGAGCCATCATCAGCTGAGCACCCTGGTTCTGACCGGTAATCCGCTGATCTTCATGGCCGAAACCAGTCTGAATGGTCCGAAAAGCCTGAAACATCTGTTCCTGATTCAGACCGGTATTAGCAATCTGGAATTCATTCCGGTGCATAATCTGGAAAATCTGGAAAGCCTGTATCTGGGCAGTAATCATATTAGTAGCATTAAATTCCCGAAGGACTTCCCGGCCCGTAATCTGAAAGTTCTGGACTTCCAGAATAATGCAATTCATTATATCAGCCGCGAAGATATGCGTAGTCTGGAACAGGCAATTAATCTGAGCCTGAACTTCAATGGCAATAATGTGAAAGGCATTGAACTGGGTGCCTTCGATAGTACCATCTTCCAGAGTCTGAACTTCGGTGGTACCCCGAATCTGAGCGTTATCTTCAATGGTCTGCAGAATAGCACCACCCAGAGCCTGTGGCTGGGCACCTTCGAAGATATTGATGATGAAGATATTAGCAGTGCCATGCTGAAAGGTCTGTGCGAAATGAGCGTTGAAAGTCTGAATCTGCAGGAACATCGCTTCAGTGATATTAGCTCAACCACCTTCCAGTGCTTCACCCAGCTGCAGGAACTGGATCTGACAGCAACCCATCTGAAAGGCCTGCCGAGTGGCATGAAAGGCCTGAATCTGCTGAAAAAACTGGTGCTGAGCGTTAATCACTTCGATCAGCTGTGCCAGATTAGCGCAGCAAACTTCCCGAGCCTGACCCATCTGTATATTCGCGGTAATGTGAAAAAACTGCATCTGGGCGTTGGTTGTCTGGAAAAACTGGGTAATCTGCAGACCCTGGATCTGAGCCATAATGATATTGAAGCAAGCGATTGTTGTAGCCTGCAGCTGAAAAATCTGAGCCATCTGCAGACCTTAAATCTGAGTCATAATGAACCGCTGGGTCTGCAGAGTCAGGCATTCAAAGAATGTCCGCAGCTGGAACTGCTGGATCTGGCCTTCACCCGCCTGCATATTAATGCACCGCAGAGCCCGTTCCAGAATCTGCACTTCCTGCAGGTGCTGAATCTGACCTATTGCTTCCTGGATACCAGCAATCAGCATCTGCTGGCCGGCCTGCCGGTTCTGCGTCATCTGAATCTGAAAGGCAATCACTTCCAGGATGGTACCATTACCAAAACCAATCTGCTGCAGACCGTGGGCAGCCTGGAAGTGCTGATTCTGAGCAGCTGCGGCCTGCTGAGTATTGATCAGCAGGCCTTCCATAGCCTGGGCAAAATGAGTCATGTTGATCTGAGCCACAATAGCCTGACCTGTGATAGCATTGATAGCCTGAGCCATCTTAAAGGTATCTATCTGAATCTGGCCGCCAATAGTATTAATATTATTAGCCCGCGTCTGCTGCCGATTCTGAGTCAGCAGAGCACCATTAATCTGTCACATAATCCGCTGGATTGCACCTGCAGTAATATTCACTTCCTGACCTGGTATAAAGAAAATCTGCATAAACTGGAAGGTAGCGAAGAAACCACCTGTGCAAATCCGCCGAGCCTGCGCGGTGTTAAACTGAGCGATGTTAAACTGAGTTGTGGC
Available Sizes
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