NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys- (DMC) -NH2
NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys- (DMC) -NH2 is an substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3) and can be easily detected at Abs/Em=350/465 nm[1].
Product Specifications
CAS Number
945414-97-1
UNSPSC
12352209
Target
MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nbd-arg-pro-lys-pro-leu-ala-nva-trp-lys-dmc-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCC)C(N[C@H](C(N[C@H](C(N)=O)CCCCNC(CC(C3=CC=C(N(C)C)C=C3O4)=CC4=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)NC(CCCCCNC7=CC=C([N+]([O-])=O)C8=NON=C78)=O
Molecular Formula
C78H111N21O16
Molecular Weight
1598.85
References & Citations
[1]D M Bickett, et al. A high throughput fluorogenic substrate for stromelysin (MMP-3) .Ann N Y Acad Sci. 1994 Sep 6:732:351-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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