Recombinant Rat Insulinlike growth factor I (rRtIGF-1)
Insulinlike growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. It shares 61% aa sequence identity with mature rat IGF-II. Circulating IGF-I is produced by hepatocytes, while local IGF-I is produced by many other tissues in which it has paracrine effects. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally.
Product Specifications
CAS Number
9000-83-3
Endotoxin
Less than 1EU/μg of rRtIGF-1 as determined by LAL method.
Purity
>97% by SDS-PAGE and HPLC analyses.
Bioactivity
Measured in a serum free cell proliferation assay using MCF7 human breast adenocarcinoma cells. The ED50 for this effect is typically 0.6-3 ng/mL.
Reconstitution
Molecular Weight
Approximately 7.7 kDa, a single non-glycosylated polypeptide chain containing 70 amino acid residues.
Storage Conditions
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China
AA Sequence
GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKSA
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Anti-ETS1 (Marker of Tumor Metastasis) Monoclonal Antibody (Clone: ETS1/1801)
Mouse Monoclonal Glutathione Synthetase Antibody (12F2) [Alexa Fluor 488]