What is the catalog number for Recombinant Human Human Trefoil Factor 3 (rHuTFF-3)?

The catalog number for Recombinant Human Human Trefoil Factor 3 (rHuTFF-3) is PR1042.

What sizes are available for Recombinant Human Human Trefoil Factor 3 (rHuTFF-3)?

Recombinant Human Human Trefoil Factor 3 (rHuTFF-3) is available in the following size(s): 1 mg, 5 µg, 20 µg.

How many pack sizes does Recombinant Human Human Trefoil Factor 3 (rHuTFF-3) come in?

Recombinant Human Human Trefoil Factor 3 (rHuTFF-3) is available in 3 different pack sizes.

Is Recombinant Human Human Trefoil Factor 3 (rHuTFF-3) in stock?

Recombinant Human Human Trefoil Factor 3 (rHuTFF-3) is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human Human Trefoil Factor 3 (rHuTFF-3)

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.

Product Specifications

CAS Number

9000-83-3

Endotoxin

Less than 1EU/μg of rHuTFF3 as determined by LAL method.

Purity

>95% by SDS-PAGE and HPLC analyses.

Bioactivity

Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 μg/ml.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

Molecular Weight

Approximately 6.5 kDa, a single non-glycosylated polypeptide chain containing 59 amino acids.

Storage Conditions

This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.