Recombinant Human B-Cell Maturation Antigen (rHuBCMA)
BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain.
Product Specifications
CAS Number
9000-83-3
Endotoxin
Less than 1EU/mg of rHuIL-1α as determined by LAL method.
Purity
>98% by SDS-PAGE and HPLC analyses.
Bioactivity
Data Not Available.
Reconstitution
Molecular Weight
Approximately 5.3 KDa, a single non-glycosylated polypeptide chain containing 50 amino acids.
Storage Conditions
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 30% acetonitrile, 0.1% TFA.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China
AA Sequence
AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Available Sizes
Frequently Asked Questions
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