What is the catalog number for Recombinant Murine Interleukin-3 (rMuIL-3)?

The catalog number for Recombinant Murine Interleukin-3 (rMuIL-3) is PR2023.

What sizes are available for Recombinant Murine Interleukin-3 (rMuIL-3)?

Recombinant Murine Interleukin-3 (rMuIL-3) is available in the following size(s): 1 mg, 2 µg, 10 µg.

How many pack sizes does Recombinant Murine Interleukin-3 (rMuIL-3) come in?

Recombinant Murine Interleukin-3 (rMuIL-3) is available in 3 different pack sizes.

Is Recombinant Murine Interleukin-3 (rMuIL-3) in stock?

Recombinant Murine Interleukin-3 (rMuIL-3) is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Murine Interleukin-3 (rMuIL-3)

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.

Product Specifications

CAS Number

9000-83-3

Endotoxin

Less than 1EU/mg of rmIL-3 as determined by LAL method.

Purity

>98% by SDS-PAGE and HPLC analyses.

Bioactivity

The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 107 units/mg.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

Molecular Weight

Approximately 15.1 kDa globular protein containing 135 amino acid residues.

Storage Conditions

This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.