Recombinant Murine Glia maturation factor beta (rMuGMF-β)
Glia maturation factor beta (GMF-β) coded by GMFb gene at chromosome 14 in mouse, is identical to human GMF-β, with the exception of two amino acid residues. It is a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family, and plays an important role in the upstream regulation of excessive production and the releasing of proinflammatory cytokines/chemokines in brain cells, leading to the destruction of oligodendrocytes, the myelin forming cells, and neurons.
Product Specifications
CAS Number
9000-83-3
Endotoxin
Less than 1EU/μg of rMuGMF-β as determined by LAL method.
Purity
>97% by SDS-PAGE and HPLC analyses.
Bioactivity
Data not available.
Reconstitution
Molecular Weight
Approximately 16.4 KDa, a single non-glycosylated polypeptide chain containing 141 amino acid residues.
Storage Conditions
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China
AA Sequence
Available Sizes
Frequently Asked Questions
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