Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Recombinant Mouse IL-1 Alpha (rMuIL-1 alpha)

IL-1 alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.

Product Specifications

CAS Number

9000-83-3

Endotoxin

Less than 1EU/mg of rMuIL-1 alpha as determined by LAL method.

Purity

>97% by SDS-PAGE and HPLC analyses

Bioactivity

Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of murine D10S cells is < 0.002ng/mL, corresponding to a specific activity of > 5.0x108 units/mg.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

Molecular Weight

Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 156 amino acids.

Storage Conditions

This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.

Host or Source

Escherichia col

Recommended Usage

This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China

AA Sequence

SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

6-Chloro-4-hydroxy-3-phenylpyridazine
OR0289 1 Pack

6-Chloro-4-hydroxy-3-phenylpyridazine

Ask
View Details
Vmn1r233 Protein Lysate (Mouse) with C-HA Tag
49642034 100 μg

Vmn1r233 Protein Lysate (Mouse) with C-HA Tag

Ask
View Details
THSD4 shRNA (m) Lentiviral Particles
sc-154258-V 200 µL

THSD4 shRNA (m) Lentiviral Particles

Ask
View Details
3- (4-Aminophenyl) -1- (4-chlorophenyl) urea
OR1047235-01 100 mg

3- (4-Aminophenyl) -1- (4-chlorophenyl) urea

Ask
View Details
3- (4-Aminophenyl) -1- (4-chlorophenyl) urea
OR1047235-02 250 mg

3- (4-Aminophenyl) -1- (4-chlorophenyl) urea

Ask
View Details
3- (4-Aminophenyl) -1- (4-chlorophenyl) urea
OR1047235-03 1 g

3- (4-Aminophenyl) -1- (4-chlorophenyl) urea

Ask
View Details