Recombinant Human Macrophage Colony Stimulating Factor (rHuM-CSF)
M-CSF, also known as CSF-1, is a four α helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. M-CSF is also essential for the survival and proliferation of osteoclast progenitors. M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.
Product Specifications
CAS Number
9000-83-3
Endotoxin
Less than 1EU/mg of rHuM-CSF as determined by LAL method.
Purity
>95% by SDS-PAGE and HPLC analyses.
Bioactivity
Reconstitution
Molecular Weight
Approximately 42.0 kDa, a covalently linked homodimer, of two 21.0 kDa polypeptide monomers (1-149 amino acid of human M-CSF) .
Storage Conditions
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2mm filtered solution in 20mM PB, containing 1% HSA and 3% Mannitol.
Host or Source
Baculovirus infected Silkworm
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China
AA Sequence
Available Sizes
Frequently Asked Questions
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