GSDMD Recombinant Rabbit mAb
Product Specifications
Background
Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D) . [provided by Alliance of Genome Resources, Apr 2022]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
DF5L; M2-4; Dfna5l; GsdmD-1; Gsdmdc1; 1810036L03Rik
Swiss Prot
Q9D8T2
Reactivity
Mouse, Rat
Immunogen
Recombinant protein of mouse GSDMD
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
53,31 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from 3T3 cells at 1:1000.
Host or Source
Rabbit
Available Sizes
Curated Selection
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