CD3 Recombinant Rabbit mAb
Product Specifications
Background
CD3 is a complex of proteins that directly associates with the T cell receptor (TCR) . The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
T3
Swiss Prot
P04234, P07766, P09693, P20963
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human CD3
Conjugation
Unconjugated
Applications
WB, IHC, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
23 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Applications Notes
Western blot analysis of extracts from Jurkat cells at 1:1000.
Host or Source
Rabbit
Available Sizes
Curated Selection
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