GPNMB Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
NMB; HGFIN; PLCA3
Swiss Prot
Q14956
Reactivity
Human
Immunogen
Recombinant protein of human GPNMB
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
95120 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from SK-BR-3 cells using BS49239 at 1: 1000.
Host or Source
Rabbit
Available Sizes
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