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Anti-GDF3 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

KFS3; MCOP7; MCOPCB6

Swiss Prot

Q9NR23

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human GDF3

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:1000

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

41 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of extracts from HepG2 cells at 1:1000.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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