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XPB Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

XPB; BTF2; TTD2; GTF2H; RAD25; TFIIH

Swiss Prot

P19447

Reactivity

Human

Immunogen

A synthetic peptide of human XPB

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

89 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of extracts from HeLa cells using it at 1:1000.

Host or Source

Rabbit

Available Sizes

Curated Selection

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