TMEM119 Recombinant Rabbit mAb
Product Specifications
Background
Plays an important role in bone formation and normal bone mineralization (PubMed:26207632, PubMed:22416756, PubMed:20025746) . Promotes the differentiation of myoblasts into osteoblasts (PubMed:22416756, PubMed:20025746, PubMed:22579779) . May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway (PubMed:21239498, PubMed:22579779) . Upregulates the expression of ATF4 which plays a central role in osteoblast differentiation (PubMed:24362451) . Essential for normal spermatogenesis and late testicular differentiation (PubMed:26207632) .
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
Obif; AW208946; BC025600
Swiss Prot
Q8R138
Reactivity
Mouse
Immunogen
Recombinant protein of mouse TMEM119
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC: 1:200
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
29 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Host or Source
Rabbit
Available Sizes
Curated Selection
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