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Glypican 3/GPC3 Recombinant Rabbit mAb

Product Specifications

Background

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2

Swiss Prot

P51654

Reactivity

Human

Immunogen

Recombinant protein of human Glypican 3/GPC3

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

40,75 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of extracts from Hela, Jurkat cells using BS48099 at 1: 1000.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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