PER3 Recombinant Rabbit mAb
Product Specifications
Background
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
GIG13; FASPS3
Swiss Prot
P56645
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PER3
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000-1:2000
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
132 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from T24, C2C12 cells and Rat heart tissue using it at 1:1000.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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