DKK1 Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
SK; DKK-1
Swiss Prot
O94907
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human DKK1
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
28-40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from PC-3 cells using it at 1:1000.
Host or Source
Rabbit
Available Sizes
Curated Selection
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