Lin28 Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
Swiss Prot
Q9H9Z2
Reactivity
Human
Immunogen
A synthetic peptide of human Lin28
Conjugation
Unconjugated
Applications
WB, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
28 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from JAR cells using it at 1:1000.
Host or Source
Rabbit
Available Sizes
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