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Lin28 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A

Swiss Prot

Q9H9Z2

Reactivity

Human

Immunogen

A synthetic peptide of human Lin28

Conjugation

Unconjugated

Applications

WB, FC, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

28 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot analysis of extracts from JAR cells using it at 1:1000.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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