Trk (pan) Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Swiss Prot
P04629, Q16620, Q16288
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human Trk (pan)
Conjugation
Unconjugated
Applications
WB, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
120-140 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from Mouse brain tissue using db11141 at 1:1000.
Host or Source
Rabbit
Available Sizes
Curated Selection
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