DGCR8 Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
Gy1; pasha; DGCRK6; C22orf12
Swiss Prot
Q8WYQ5
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human DGCR8
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
120 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of DGCR8 in K562, C6,3T3 cell lysates using DGCR8 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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