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Transglutaminase 2 Recombinant Rabbit mAb

Product Specifications

Background

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

TGC; TG (C)

Swiss Prot

P21980

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human Transglutaminase 2

Conjugation

Unconjugated

Applications

WB, IHC, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

77 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Transglutaminase 2 in Rat Brain lysates using Transglutaminase 2 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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