WAVE 1 Recombinant Rabbit mAb
Product Specifications
Background
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP) -family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
WAVE; SCAR1; WAVE1
Swiss Prot
Q92558
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human WAVE 1
Conjugation
Unconjugated
Applications
WB, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of WAVE 1 in Rat Brain, C6,3T3, Hela cell lysates using WAVE 1 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
Curated Selection
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