C3 Recombinant Rabbit mAb
Product Specifications
Background
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
Swiss Prot
P01024
Reactivity
Human
Immunogen
A synthetic peptide of human C3
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
120 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of C3 in K562, Hela cell lysates using C3 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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