GRK2 Recombinant Rabbit mAb
Product Specifications
Background
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
BARK1; ADRBK1; BETA-ARK1
Swiss Prot
P25098
Reactivity
Human
Immunogen
A synthetic peptide of human GRK2
Conjugation
Unconjugated
Applications
WB, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of GRK2 in Hela, A549, HL-60, U2OS cell lysates using GRK2 antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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