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Cytochrome P450 Reductase Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

CPR; CYPOR; P450R

Swiss Prot

P16435

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human Cytochrome P450 Reductase

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

77 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Cytochrome P450 Reductase in K562, Rat Brain, C6,3T3 cell lysates using Cytochrome P450 Reductase antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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