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Proteasome 20S alpha 2 Recombinant Rabbit mAb

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

MU; HC3; PSC2; PMSA2

Swiss Prot

P25787

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human Proteasome 20S alpha 2

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

26 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of Proteasome 20S alpha 2 in K562, C6, Hela cell lysates using Proteasome 20S alpha 2 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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