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PAX6 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

AN; AN2; FVH1; MGDA; WAGR; ASGD5; D11S812E

Swiss Prot

P26367

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human PAX6

Conjugation

Unconjugated

Applications

WB, IHC, FC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

47 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of PAX6 in Rat Brain lysates using PAX6 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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