Fyn Recombinant Rabbit mAb
Product Specifications
Background
Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
AI448320; AW552119
Swiss Prot
P39688
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of mouse Fyn
Conjugation
Unconjugated
Applications
WB, IHC, FC, IP
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
61 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of Fyn in Rat Brain lysates using Fyn antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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