HBEGF Recombinant Rabbit mAb
Product Specifications
Background
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
DTR; DTS; DTSF; HEGFL
Swiss Prot
Q99075
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human HBEGF
Conjugation
Unconjugated
Applications
WB, IHC
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
23 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot detection of HBEGF in K562, C6,3T3, Hela cell lysates using HBEGF antibody (1:1000 diluted) .
Host or Source
Rabbit
Available Sizes
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