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HBEGF Recombinant Rabbit mAb

Product Specifications

Background

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

DTR; DTS; DTSF; HEGFL

Swiss Prot

Q99075

Reactivity

Human, Rat

Immunogen

A synthetic peptide of human HBEGF

Conjugation

Unconjugated

Applications

WB, IHC

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

23 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of HBEGF in K562, C6,3T3, Hela cell lysates using HBEGF antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

Curated Selection

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